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Quotes - Engineering - SalesAdvantage Chillers for Storage of Biological Reagents &Blood
Even minor temperature fluctuations in blood storage or reagent refrigeration can cause hemolysis, protein denaturation, or loss of bioactivity. Advantage biostorage chillers use dual-redundant compressors, 316L stainless glycol loops, and HEPA-filtered air to maintain 4.0°C (±0.1°C) for blood, –30°C (±0.5°C) for plasma, and –80°C (±1.0°C) for stem cells—ensuring AABB, CAP, and 21 CFR Part 11 compliance with full audit traceability.
Applications
- Blood Bank Refrigeration: Chillers hold 4.0°C ±0.1°C in 1,200L units, protecting 500+ RBC units and supporting 42-day shelf life per FDA standards.
- Plasma &Cryoprecipitate Freezers: –30°C cascade systems with uniform airflow ensure <1°C variation across 400-bag storage, enabling 7-year viability.
- Reagent &Antibody Cold Rooms: 2–8°C glycol loops with humidity control preserve monoclonal antibodies and PCR reagents in 300 ft³ walk-ins.
- Ultra-Low –80°C Biobanks: Redundant chillers + LN2 backup protect 100,000+ vials with <3-minute recovery after door openings.
- Stem Cell &Tissue Storage: –196°C vapor-phase LN2 systems with chilled overwrap maintain gradient-free conditions for long-term HSC banking.
Portable Process Chillers
Flexible Spot Cooling
- 1–40 Ton Mobile Units
- Quick-Connect Camlock Fittings
- Digital Flow & Pressure Readouts
Central Chiller Plants
High-Capacity Modular Systems
- 50–1,000+ Ton Scalability
- N+1 Redundancy Options
- Remote Monitoring & Predictive Alerts
The Benefits of Advantage Chillers for Storage of Biological Reagents & Blood
In transfusion medicine and biobanking, temperature control is the foundation of safety and research integrity. A regional blood center suffered a $2.1M loss after a 4-hour excursion above 6°C destroyed 7,500 platelet units. After installing an Advantage dual-redundant blood bank chiller with NIST-traceable sensors and automatic LN2 failover, they achieved 100% compliance for 30+ months, reduced waste by 96%, and passed every AABB and FDA inspection with zero deviations.
Advantage biostorage chillers are engineered with electropolished 316L stainless circuits, 0.2 µm HEPA filtration, and FDA-approved non-toxic glycol. PLCs with 21 CFR Part 11 electronic records integrate with Cerner, Epic, and LIMS platforms, while triple-redundant power (UPS + generator + LN2) ensures <30-second failover. Optional CO2 incubator integration maintains cell culture stability during sample transport.
From small hospital blood banks to global biobanks storing millions of irreplaceable samples, Advantage delivers the precision, redundancy, and documentation needed to protect life-saving materials—unit after unit, vial after vial.
